I. Course Identification
Discipline:       Biology
Title & Number:   Principles of Biology I (Biology 111)
Credit Hours:     4
Contact Hours:    6    MWF, 9:05-:10:00 (D-116)
                       T, 8:00-11:00 or 12:20-3:25 (C-306)
Instructor:     William Camelet,PhD * My Homepage
Office Number:    C324E   Office Hours See Schedule
Voice Mail:       (269)927-8100, x5076, 1-800-252-1LMC
Email:         camelet@lakemichigancollege.edu
Prerequisite:     (E,M,R)The student should have completed
                  two years of high school laboratory science
                  with a "C" average and at least one of these
                  years being in biological science, or
                  Biological Science 101 or its equivalent.
Semester & Academic Year:  Fall, 2003

II. Textbooks and/or Equipment/Supplies

Required: Campbell, Neil,and Jane B.Reece,  2002,
       Biology, Benjamin/Cummings
                     Vodopich Darrell S. & Randy Moore, 2002
      Biology Laboratory Manual, WCB/McGraw-Hill

IV. General Education Areas Met:
     This course contributes to the fulfillment of the following
     General Education Requirements:
     "2" Communication
     "3" Critical Thinking
     "5" Mathematics
     "6" Science
     "7" Technology
     "8" Wellness

     Each General Education Requirement fulfillment is indicated
     by number in course goals.

 V.  Goals and Objectives

     Upon the completion of each course unit, students
     will/shall be able to:

                  Unit 3 Genetics
      E. Explain the classic mechanisms of inheritance.
     ("2", "3" "6", "7")
     22. Explain Mendel's first law (Law of Segregation) and
         second law (Law of Independent Assortment).
     23. Define: gene, allele, locus, dominant, recessive,
         codominant, phenotype, genotype, homozygous,
         heterozygous monohybrid cross and dihybrid cross.
     24. Explain sex-linked traits and autosomal traits.
     25. Define epistasis, pleiotropic genes, and lethal genes.
     26. Deduce genotypes and probability for dominance,
         recessiveness, codominance, multiple alleles, sex
         linkage and polygenes.
     27. Explain linked genes, crossing over, frequency
         of recombination and gene mapping.
  F. Explain how genetic information stored in DNA molecules
     is used to assemble protein molecules.
     ("2", "3" "6", "7")
     28. Describe the Watson Crick Model of DNA, the base
         pairing rule, and the  mechanism of replication.
     29. Understand the "central dogma" in the gene-enzyme
         relationship; give the details of transcription,
         post transcriptional modification, and translation.
         Note all RNA types and their role in the synthesis
         of specific polypeptide chains.
  G. Describe the control of gene expression at the
     transcriptional level in prokaryotes and eukaryotes.
     30. Define the terms promoter, operon and operator.
     31. Describe gene mutation, the frequency of mutation,
         and chromosomal aberrations such as monosomy
         and trisomy.
     32. Describe the relationship between mutations and
         cancer.
     33. Define oncogenes and describe their possible function.
     34. Define plasmids and transposons
  H. Explain some of the current techniques used for DNA technology.
      ("2", "3" "6", "7")
     35. Describe the polymerase chain reaction.
     36. Describe the role of restriction endonucleases and
         DNA ligase in genetic engineering.
     37. Describe the steps in DNA fingerprinting.
     38. Describe the use of transgenic bacteria and plants.

  I. Explain the vertebrate non-specific defense mechanism and
     the immune mechanism.
     ("2", "3" "6", "7")
     39. Describe phagocytosis and inflammationand define
         complement and interferon
     40. Contrast the maturation, structure and function
         of B and T lymphocytes.
     41. Describe the structure and function of an antibody.
     42. Describe the different type of T cells and describe
         the function of each.
  J. Explain chemical signaling in animals.
     ("2", "3" "6", "7")
     43. Describe pheromones and local regulators
     44. Describe how hormones work.
     45. Compare the modes of action of steroid and peptide
         hormones.
     46. Describe the major endocrine glands, their hormones and
         functions.
  K. Explain the stages in animal development.
      ("2", "3" "6", "7")
     47. Describe the process of fertilization.
     48. Describe cleavage and the early stages of
         embryology to the gastrula and name an organ system
         derived from each of the primary germ layers
        (ectoderm, mesoderm, endoderm).
     49. Describe the four extraembryonic membranes of
         birds and reptiles and explain the function of
         the placenta in mammals.
     50. Describe homeotic genes and their function.
     51. Describe induction in differentiation

VI. Expected Student Outcomes

During the semester you will be assessed for learning outcomes. Some questions in the final exam will be used for assessment.  Additional assessment will involve the construction of concept maps over certain topics. Not all of the student concept maps will be graded.  Assessments will be used to gauge comprehension and the data may lead to improvement of instructional techniques.

VII.   Instructional Methodology
        A. Lecture presented on PowerPoint.
        B. Chalk reviews and discussion.
        C. Course web pages, maintained on LMC internet, contains
           all topics and information presented in classroom.
        D. Supplemental material and links to study aids and
           biology games are also available on course web pages.
        E. Interactive programs will be available in the Science
           Computer Lab (C118)
        F. Weekly laboratory exercises.

VIII   Writing Across The Curriculum Strategy
Students are expected to write lab reports and quiz answers                using appropriate grammar, sentence structure and spelling.

IX. Grading Criteria And Requirements
   For a student to get credit and a letter grade, he/she
   must take exams and quizzes at scheduled times and
   achieve the minimum level scores on these tests as
   indicated in the grading scale. Good writing skills
   must be demonstrated on exams and quizzes.

A. The Exams are as follows:

1. Three hour exams (100 points each).
   Each exam will be approximately 60% objective
   (multiple choice, matching, true or false) and
   40% written (essay, short answers, definitions).
   Note dates on Lecture Schedule. The questions are
   taken from the objectives outlined in  this syllabus.

2. Six announced quizzes over lab or lecture material
   (10 points each). Only the five highest scores
   will be counted, with your lowest score dropped. If
   you are absent for a quiz or arrive late to take the
   quiz it will be considered your lowest.

3. Laboratory exams will be given as a midterm
   and a final (100 points each). These exams will
   cover the laboratory exercises. The material
   is from the lab manual and lab reports and a study
   guide for all laboratory terms will be provided for
   each assigned lab exercise in the lab manual. Note
   dates on Laboratory Schedule (page 12).

4. A comprehensive final exam (100 points) will
   conclude the course and will include objectives
   from all units but specifically from the last unit.
   The format is objective (includes multiple choice,
   matching and/or true and false questions).

5. NOTE: In the event of the school being closed (snow
   day, etc.) when a test (lecture or lab) is scheduled,
   you should be prepared for that test, at  the next
   regularly scheduled class or lab period.

   Critical Thinking Skills in the scientific method
   will be emphasized and assessed.

X. Grading Scale
 

B. The grade for the course is determined on the
   following percentage of total points:
 

XI. Make-up Policy
      Make up Exams:  If a test is missed the student must
      make arrangementswith the instructor to make up the
      test outside of class time. The make up test should
      be completedwithin a week of the scheduled exam.
      Make-up tests will be combination of objective, oral
      or essay. There will be no make up for a  missed quiz.

XII. Attendance Policy/Withdrawal Policy
    A. The class attendance policy is the same as the
       collegepolicy as stated in the College Catalog.
       "It is consistent with the college philosophy that
       regular class attendance is necessary if the student
       isto receive maximum benefits from the course.
       Studentsare expected to attend every class and
       laboratoryperiod for which they have registered."
       "Two weeks of consecutive absences or failure to
       attend20% of the scheduled semester contact hours
       for aclass, makes a student subject to dismissal
       from the class at the option of the instructor."

          B. Religious Accomodation:  Mindful of the diverse student
       body that Lake Michigan College serves, and the varied belief
       systems that its students represent, the College will make a
       reasonable effort to accommodate students who need to be
       excused from classes for the observance of religious
       holidays.  This policy does not apply to students who knowingly
       register for classes scheduled to meet on days that
       consistently conflict with their day of worship, e.g., a
       student who signs up for Saturday classes when the student
       normally worships on Saturday.

    C. Dropping the Course   The current college policy is that
       "Students who withdraw from class through the twelfth week
       of the semester (four weeks in spring or summer session)
       will be assigned a grade of W.  Beyond the twelfth week
       of the semester, students who withdraw  will be assigned
       a grade of E."
       The last day to withdraw from class is November 18,2003.

XIII. Assignment Schedule
   The Assignment Schedule will be followed as closely as
   possible; however, changes may be made at the
   instructor's discretion.

.